Programme

09:30 OC-06-01
Targeting the central cavity of TASK-1 K2P channels: A novel mechanism for direct activation with therapeutic drugs
Thomas Baukrowitz; Kiel, Germany

09:45 OC-06-02
Single-channel activity of two K+-selective channelrhodopsins at femtosiemens resolution
Klaus Benndorf, Ralf Schmauder, Peter Hegemann; Jena, Germany, Berlin, Germany

10:00 OC-06-03
Modulation of gating in an autonomous K+ channel selectivity filter
Nils Drexler, Lena Diederich, Ulf-Peter Hansen, Indra Schroeder; Jena, Germany, Kiel, Germany

10:15 OC-06-04
Mechanisms of volume-regulated anion channel (VRAC) activation: the LRRC8A intracellular subdomain couples conformational dynamics to pore opening
Sara Bertelli, Lu Wang, Malte Klüssendorf, Michael Pusch, Raimund Dutzler, Tobias Stauber; Genova, Italy, Zürich, Switzerland, Hamburg, Germany

10:30 OC-06-05
Optogenetic control of RyR2 combined with automatic cell segmentation and analysis enables high-content screening of RyR2-modulating compounds in HEK293 cells
Wanchana Jangsangthong, Jan V. Otte, Judith Sofie Langen, Miroslav Dura, Housen Li, Martina Krüger, Alexander Gottschalk, Stephan E. Lehnart, Axel Munk, Philipp Sasse; Bonn, Germany, Göttingen, Germany, Düsseldorf, Germany, Frankfurt a. M., Germany

10:45 OC-06-06
Sub-Millivolt Voltage Imaging Reveals Gap Junction-Mediated Bioelectric Contact Inhibition
Philipp Rühl, Rama Hussein, Stefanie Reuter, Konrad S. Frahnert, Anagha G. Nair, Ralf Mrowka, Roland Schönherr, Stefan H. Heinemann; Jena, Germany