Programme
Details
Ian Karan Hörsaal (N55)
14:25–14:55
KN-04 | FLOW of Proteins
Activity-driven proteasome complexes: Bridging molecular mechanisms with organ physiology and translation
Activity-driven proteasome complexes: Bridging molecular mechanisms with organ physiology and translation
Prof. Seth Margolis
Johns Hopkins University, Baltimore, USA
FLOW of Proteins
“Activity-driven proteasome complexes: Bridging molecular mechanisms with organ physiology and translation”
KN-04
Prof. Seth Margolis is a neuroscientist whose research elucidates key mechanisms of synaptic regulation and neuronal plasticity, particularly the role of the membrane proteasome in controlling local protein degradation at synapses. This work offers new insights into how neural circuits adapt and how disruptions contribute to disorders such as Alzheimer’s disease, autism, and other neurodegenerative or neurodevelopmental conditions. With the concept of the membrane proteasome, Prof. Margolis has opened an entirely new field of research.
