Programm

P18-01
Dynamic coupling reloaded - functional characterization of disease-related KCND2 variants affecting Kv4.2 channel inactivation gating
Anna Babenhauserheide, Yongqiang Zhang, Stefan Kindler, Robert Bähring; Hamburg, Germany

P18-02
Potassium channel modulation enhances KRAS-targeted therapy in PDAC
Weronika Wilczak, Albrecht Schwab, Zoltan Pethö; Münster, Germany

P18-03
Biophysical properties of Kv7/KCNQ/M-channels in hippocampal mossy fibre boutons
Luise Wehle, Ricardo Murphy, Henrik Alle, Johan F. Storm, Jörg Rolf Paul Geiger; Berlin, Germany, Oslo, Norway

P18-04
KCNH3 loss-of-function variant associated with epilepsy and neurodevelopmental delay enhances Kv12.2 channel inactivation
Christiane K. Bauer, Frederike L. Harms, Robert Bähring; Hamburg, Germany

P18-05
Investigating the mechanisms of KvS-mediated trafficking in KCNQ Channels
Rajeshwari Bisen, Aparna Renigunta, Dominik Oliver, Vijayaram Kumar Renigunta; Marburg, Germany

P18-06
Selective control of intrinsic in vitro bursting by somato-dendritic Kv7 channels in VTA dopamine neurons projecting to the medial shell of the nucleus accumbens
Tabea Ziouziou, Emanuel Lopes, Christopher Knowlton, Carmen Canavier, Stephanie Cragg, Jochen Roeper; Frankfurt a. M., Germany, Oxford, United Kingdom, New Orleans, United States

P18-07
Kv4 channel gating modulation by pathogenic KCND variants affecting the pore helix
Pia Ullmann, Fabian Schönewald, Stefan Kindler, Robert Bähring; Hamburg, Germany

P18-08
Selective inhibition of the Kv2.1/6.4 heteromeric potassium channel by Riluzole
Debanjan Tewari, Klaus Benndorf, Indra Schröder; Jena, Germany

P18-09
Conformational basis of TREK channel activation: revisiting the role of the down–up transition and the lipid-occluded pore
Marianne Musinszki, Chun Kei Lam, Edward Mendez Otalvaro, Friederike Schulz, Elena B. Riel, Anthony Ogwo, Kristin Rathje, Lea C. Neelsen, Bert de Groot, Marcus Schewe, Thomas Baukrowitz; Kiel, Germany, Göttingen, Germany, New York, United States

P18-10
Analysing the voltage dependences of A-type potassium channel gating considering GHK rectification
Robert Bähring, Anna Babenhauserheide, Thomas Meurer, Christiane K. Bauer; Hamburg, Germany

P18-11
Targeting the modulator pocket in K2P channels: New activators for the family member TRAAK
Chaimae Benkerdagh, Jonathan Ralph, Nathaniel Smith, Han Sun, Thomas Baukrowitz, Marcus Schewe; Kiel, Germany, Berlin, Germany

P18-12
Functional Role of K2P Channels in the Regulation of Tone in Systemic Arteries
Lara Maria Astrid Heinrich, Rudolf Schubert; Augsburg, Germany

P18-13
Functional analysis of a pathogenic KCND2 variant affecting the linker between voltage-sensor and pore module
Thomas Meurer, Stefan Kindler, Robert Bähring; Hamburg, Germany

P18-14
The Sea Urchin TMEM175 Channel: A Regulator of Vesicular pH and K⁺?
Caroline Rott, Ornina Merza, Sönke Cordeiro, Marianne Musinszki, Marian Hu; Kiel, Germany