Programm

P13-01
Distinct cardiac proteomic and phosphoproteomic profiles distinguish obesity-independent heart failure with preserved versus reduced ejection fraction
Franziska Koser, Mahmoud Abdellatif, Theresa Bock, Marcus Krüger, Simon Sedej, Wolfgang A. Linke; Münster, Germany, Graz, Austria, Cologne, Germany, Köln, Germany

P13-02
Loss of the deubiquitinase OTUB1 induces an HFpEF-like phenotype in mice altering sarcomere-, cytoskeleton- and MAPK signaling- associated proteins
Nina Oechsler, Sarah Costantino, Amalia Ruiz-Serrano, Yulia L. Volkova, Alexander Akhmedov, Nicole Olgunelma, Manuela Gesell Salazar, Leif Steil, Stefan Simm, Uwe Völker, Francesco Paneni, Carsten C. Scholz; Greifswald, Germany, Zurich, Switzerland, Coburg, Germany

P13-03
HFpEF, HFrEF, or maybe HFimpEF? On the Role of Ventricular Deformation and Echocardiographic Analysis Methods in the Classification of Heart Failure in Diabetic Mice
Andre Heinen, Axel Gödecke; Düsseldorf, Germany

P13-04
The SGLT2 inhibitor, Dapagliflozin, Decreases Mitochondrial Oxygen Consumption in a Murine Model of Heart Failure with Preserved Ejection Fraction
Anna Vingborg, Elina Kovalenko, Markus M. Rinschen, Tina Myhre Pedersen, Vladimir V. Matchkov; Aarhus, Denmark

P13-05
Selective titin cleavage disrupts cardiac mechanical homeostasis to drive diastolic dysfunction and fibroblast activation
Johanna Freundt, Paulina Hartmann, Andreas Unger, Christine Löscher, Franziska Koser, Annika J. Klotz, Lydia Wachsmuth, Michaela Door, Susanne Hille, Richard Holtmeier, Jonathan Kirk, Cornelius Faber, Verena Hoerr, Oliver J. Müller, Wolfgang A. Linke; Münster, Germany, Chicago, United States, Kiel, Germany

P13-06
Coronary flow reserve and capillary density is preserved in mice with HFpEF
Katrine Hegelund Rasmussen, Eliott Hamann, Oliver Holm, Thomas Jepps, Ylva Hellsten, Morten B Thomsen; Copenhagen, Denmark

P13-07
Myotoxin II, a snake venom Lys49 phospholipase A2 homolog, induces calcium release from intracellular stores in rat cardiomyocytes
Isabel Quirós-Gutiérrez, Jia-Hao Zhao, Kathrin Kowalski, Bruno Lomonte, Julián Fernández, José María Gutiérrez, Natalie Weber, Theresia Kraft, Alfredo J. López Dávila; Hannover, Germany, San José, Costa Rica

P13-08
In vivo evaluation of cardiomyocyte-specific AKAP7 gamma/delta deficiency in the mouse
Karoline Morhenn, Hariharan Subramanian, Helga Vitzthum, Viacheslav O. Nikolaev, Heimo Ehmke; Hamburg, Germany

P13-09
Functional investigation of dilated cardiomyopathy mutation in β-cardiac myosin light chain 2
Rima Sarkar; Hannover, Germany