Programme

Chair: Erik A. Richter, Copenhagen, Denmark

09:30 GS-01-01
Interaction of Exercise and Insulin regulating Muscle Metabolism
Erik A. Richter, Copenhagen, Denmark

09:55 GS-01-02
Molecular Integration of Exercise and Insulin Signaling by RabGAP Proteins
Alexandra Chadt, Düsseldorf, Germany

10:15 GS-01-03
Dietary Medium-Chain Triacylglycerols in Metabolic Regulation
Maximilian Kleinert, Nuthetal, Germany

10:40 GS-01-04
The systemic effects of cancer-induced GDF15
Steffen H. Raun, Copenhagen, Denmark

Short description:
This symposium will address the critical role of skeletal muscle in systemic metabolic regulation. Muscle metabolism influences glucose homeostasis, lipid utilization, and energy balance, and is profoundly shaped by both physical activity and dietary intake. Exercise enhances mitochondrial function, insulin sensitivity, and substrate flexibility, while nutrition modulates protein synthesis, recovery, and metabolic adaptation. Cancer may disrupt muscle integrity and insulin sensitivity and may lead to cachexia, but the underlying mechanisms are still unresolved. This symposium will foster interdisciplinary dialogue, highlight translational opportunities, and advance strategies for optimizing muscle as well as whole body metabolism.